Join Us

South San Francisco, California, United States
Senior Research Associate - Novel Combination Immunotherapies
Stemness Research

At Lyell, our vision is to develop curative cell-based immunotherapies for solid tumor cancers.  We have innovative science originating from our founder’s world class labs and a unique and disruptive approach to research and development. Our company is first and foremost focused on understanding the science.  We are a learning organization, dependent on deep collaborative relationships between our colleagues, partners, and founders.  Our culture is based on Science, Respect, Courage and Collaboration, and it reflects who we are and the environment we are creating.

The Research Associate II will work collaboratively with supervising Scientists and the broader research team to develop and perform the standard assays for their specific project. Function semi-independently to troubleshoot problems that arise within these assays and think creatively to improve upon existing protocols. Work closely with colleagues in other areas of research and can involve more complex and specialized areas of a specific project. Responsible for keeping abreast of current publications relative to methods, techniques, and developments within the area of research.  Responsible for carrying out specific experiments, usually confined to a single greater Research and Development aim in one technical area


  • Can execute experiments independently, requires assistance in the design and analysis of experiments
  • Collaborate internally with Scientists and other research associates to interrogate our novel therapies
  • Setup and maintenance of a highly functioning lab; can be responsible for more in depth maintenance and function of specialized equipment
  • Analysis and presentation of experimental data to project teams
  • Generation and maintenance of electronic lab notebook reports


  • BSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 5 years’ experience within the area of focus
  • MSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 3 years’ experience within the area of focus


  • Experience with basic molecular biology protocols (i.e. PCR, Western, RT-PCR, basic cloning)
  • Experience using and analyzing common immunology and oncology assays related to the specific project
  • Experience with flow cytometry assays and analysis; more complex analysis and cell sorting experience a plus
  • Proficient in sterile tissue culture technique and experience working with human cells 
  • Experience in data production and reporting for IND-enabling studies
  • Experience recording data in electronic notebook
  • Additional specific experience related to the area of focus may be required

Knowledge, Skills and Abilities:

  • Understands the theoretical basis and experimental objectives and how they fit into the overall project goals
  • Knowledgeable and proficient in a range of technical skills within their area of research
  • Highly proficient in using Microsoft Office (Word, Excel, PowerPoint) and data analysis software packages (Prism, Flow Jo, Spotfire, Geneious, etc) 
  • Effectively communicate and discuss results with other scientists on the team 
  • Ability to work in a matrixed environment 
  • General comfort in learning to work with new software and automated lab equipment

 At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse, and inclusive culture for all employees.

Lyell is proud to be an equal opportunity employer and does not discriminate based on race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status, or any other characteristics protected under applicable federal, state, and local laws.

The Company complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.  This position requires you to work onsite at the Company’s facilities and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law).  Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law.  The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine.  The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited or unable to access or use this online application process and need an alternative method for applying, please contact us at

to Top