Process Sciences
Seattle, Washington, United States

Research Associate II, Process Development

At Lyell, our vision is to develop curative cell-based immunotherapies for solid tumor cancers. We have innovative science originating from our founder’s world class labs and a unique and disruptive approach to research and development. Our company is first and foremost focused on understanding the science. We are a learning organization, dependent on deep collaborative relationships between all of our colleagues, partners and founders. Our culture is based on Science, Respect, Courage and Collaboration and it reflects who we are and the environment we are creating.

Position Summary:

We are recruiting a Research Associate II for our Process Lifecyle team within the Process Development organization. The Research Associate will work collaboratively with supervising Scientists and the broader team to perform unit operations according to project workflows. Function semi-independently to troubleshoot problems that arise within these operations and think creatively to improve upon existing workflows. Work collaboratively and cross-functionally with research and LyFE Manufacturing Facility teams. Responsible for carrying out specific experiments & operations, for the development & optimization of cell therapy production processes for our novel T-cell therapies.

Essential Functions:

  • Execute experiments to support development of T-cell production processes
  • Support process design and process transfer activities
  • Deliver data analysis, presentations, prepare technical reports for broader project teams
  • Participate in the evaluation and implementation of new process technologies
  • Participate in and support investigations for process transfer with LyFE personnel
  • Contribute to building a culture that encourages continuous learning, innovation, and collaboration

Preferred Experience:

  • 2-4 years’ experience with mammalian cell culture
  • Experience with cell therapy and/or process development
  • Proficient in sterile tissue culture technique and experience working with human cells
  • Experience recording data in electronic notebook
  • Proficient performing and analyzing common immunology and oncology assays


  • BSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 5 years’ experience within the area of focus
  • MSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 3 years’ experience within the area of focus

 Preferred Additional Skills:

  • Proven ability to work independently and collaboratively among cross-functional teams
  • Ability to work efficiently, prioritize workflow, meet deadlines and balance competing priorities in a matrixed environment
  • Plan experiments and manage time independently
  • Comfortable in learning new protocols, working with new software and automated lab equipment
  • Effective oral and written communication skills
  • Basic skills using Microsoft Office (Word, Excel, PowerPoint) and data analysis software packages Prism, JMP, Flow Jo, Spotfire, Geneious, etc
  • Ability to think critically, design experiments & troubleshoot problems as they arise

Lyell offers its employees a range of compensation and benefits. To assist you with your decision to apply for this role, the following decision to apply for this role, the following information and links to our site highlight our competitive market position and support to our employees and their dependents.

The salary range for this position is $90,000 and $105,000, annually, with the opportunity to earn an annual bonus. The salary range is an estimate, and the actual salary may vary based on Lyell’s compensation practices and an applicant’s qualifications and experience. Employees are also eligible to participate in Lyell’s Equity Incentive Plan.

Our Employee Benefits program is extensive and includes subsidized medical, dental and vision plans from your first day of employment, FSA, Company provided Life and AD&D Insurance as well as STD and LTD Insurance, ESPP, a 401(k) Plan with Company match, mass transit commuter benefits, cell phone reimbursement and a range of supplemental benefits that you may choose to elect. Our paid time-off benefits currently include 18 days’ vacation, 9 day’s sick leave, 8 observed holidays as well as a floating holiday. We also have a summer and a winter office shutdown. More information on our extensive benefits offering can be found here.

At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse and inclusive culture for all employees.
Lyell is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws.
The Company complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.  This position requires you to work onsite at the Company’s facilities and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law).  Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law.  The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine.  The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.”
We’ve learned from experience that some of the best people don’t always match our requirements perfectly - if you’re interested and think you could fit, please don’t hesitate to apply.
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