Corporate IT
South San Francisco, California, United States

Vice President, Information Technology & Information Sciences

Using living cells to treat – and sometimes even cure – cancer is one of the most dramatic advances in modern medicine. Patients with hematologic malignancies have been successfully treated with cell therapies. However, these profound results have not yet been achieved in patients with solid tumors, representing approximately 90% of all cancers. At Lyell, our goal is to change that. We are a clinical-stage T-cell reprogramming company advancing a diverse pipeline of cell therapies for solid tumors based on our innovative technologies. We were founded by cell therapy pioneers whose decades of research elevated the broader understanding of T-cell biology and its interaction with cancer. In our quest to defeat solid tumors, we have built a fully integrated company capable of discovering new technologies, translating science into therapies, manufacturing cell therapy products, and clinically evaluating them in patients. Our culture is based on Science, Respect, Collaboration, and Courage and reflects who we are, the environment we create, and our mission's urgency.
Position Summary

The individual in this role will provide strategic leadership for the Information Technology and Information Sciences teams across the organization. In collaboration with executive leadership, this role provides the enterprise-wide vision and strategy for all data management, enterprise applications, cloud infrastructure, support, cybersecurity/security initiatives and vendor/consultant relationships across Lyell, ensuring that Lyell’s IT and IS platforms meets the needs of Lyell’s teams across all functions. This role is accountable for securing Lyell’s data against inside and outside threats.  This role can be based out of our Seattle office.  

Key Role and Responsibilities

  • Partner with all functions to ensure that digital needs are met and data and information is being managed in accordance with Lyell’s data governance and security policies.
  • Responsible for corporate IT foundational services: networking, video conferencing, communications, and desktop productivity tools.
  • Development, implementation and operations of information systems, enterprise applications, IT support infrastructure, cloud technologies and ensuring that Lyell’s data is secured against both inside and outside cybersecurity threats.
  • Conduct relevant risk assessments and mitigations for business continuity, data security, data integrity and compliance.
  • Establish operational best practices, controls and metrics across the function.
  • Hire, develop and retain top-rate technical and software engineering teams.
  • Develop and actively manage annual budgets, full-time and contract hiring.
  • Partner with Lyell’s Chief Legal Officer on data privacy efforts.

Information Technology

  • Provide senior leadership to the enterprise's cloud infrastructure, information technology and cybersecurity programs and teams.
  • Develop, implement and monitor a strategic, comprehensive enterprise information security and IT risk management program, ensuring Lyell’s data is protected from internal and external threats.
  • Provide leadership and support for Lyell’s Helpdesk, IT Operations, and Application Sciences teams.
  • Develop, implement and monitor a strategic, comprehensive enterprise information security and IT risk management program.
  • Lead the design, development and implementation of technical and organizational controls to meet various compliance obligations such as GxP, HIPAA, CCPA, GDPR and SOX.
  • Own and lead Lyell’s cybersecurity incident response including planning, management documentation and reporting.
  • Participate in and prepare evidence and response for security related topics in compliance and internal/external audits.
  • Provide oversight to the selection and development of critical applications and technologies.

Information Sciences

  • Define and deploy high quality solutions to ensure data and analytics support prioritized scientific and clinical outcomes; maximize synergies between data, analytics and automation.
  • Build strategy and solutions for automatically acquiring data from instruments, monitoring instruments, and ensuring data traceability.
  • Implement cloud systems leveraging advanced analytics on integrated manufacturing, clinical, and research data to identify patterns of risk and opportunity.
  • Implement systems for the management, governance, scalability, and quality of data, including an enterprise data model, data mapping and integration across the enterprise.
  • Implement scalable, modular lab automation systems in support of Lyell’s scientific priorities, to scale Lyell’s lab operations, and to ensure production and capture of high-quality data.
  • Continue to develop strategic relationship with AWS.

Preferred Education & Experience:

  • Bachelor’s Degree with a minimum of 17 years’ experience; or Master’s Degree with a minimum of 15 years’ experience
  • 15+ years of experience in an Information Technology role
  • 10+ years in a leadership role leading technical teams on complex projects, in a start-up environment and/or high growth organization
  • Deep experience designing, building and operating production systems on AWS
  • Proven experience operating mission-critical business systems in a highly compliant environment
  • Deep experience building robust and scalable systems that generate high quality, reproducible data and insights
  • Experience with building automated lab systems

Knowledge, Skills and Abilities:

  • A seasoned leader who demonstrates sound business judgment, people leadership, while instilling best practices supported by analysis, data and metrics.
  • Experienced leader, adept at working directly with all levels of an organization, including the Executive Committee, governance bodies and Board of Directors.
  • Proven ability to partner successfully with all functions across the company (Research, Clinical Development, Technical Operations, Legal, Finance, People Team).
  • Proven ability building and instilling a customer service and problem-solving approach.
  • Strong technical foundation in security, compliance, networking, storage and computing both on premise and in the cloud, enterprise-wide applications.
  • Thorough understanding of the evolving cybersecurity landscape, threats and risks.
  • Strong understanding of modern software development practices and technologies.
  • Proven capabilities in designing, building, and evolving data and analytics infrastructure and solutions on the cloud.
Lyell offers its employees a range of compensation and benefits. To assist you with your decision to apply for this role, the following decision to apply for this role, the following information and links to our site highlight our competitive market position and support to our employees and their dependents.
The salary range for this position is to $288,000.00 to $350,000.00 annually, with the opportunity to earn an annual bonus. The salary range is an estimate, and the actual salary may vary based on Lyell’s compensation practices and an applicant’s qualifications and experience. Employees are also eligible to participate in Lyell’s Equity Incentive Plan.
Our Employee Benefits program is extensive and includes subsidized medical, dental and vision plans from your first day of employment, FSA, Company provided Life and AD&D Insurance as well as STD and LTD Insurance, ESPP, a 401(k) Plan with Company match, mass transit commuter benefits, cell phone reimbursement and a range of supplemental benefits that you may choose to elect. Our paid time-off benefits currently include 18 days’ vacation, 9 day’s sick leave, 8 observed holidays as well as a floating holiday. We also have a summer and a winter office shutdown. More information on our extensive benefits offering can be found here.
At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse and inclusive culture for all employees. Lyell is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws.
We’ve learned from experience that some of the best people don’t always match our requirements perfectly - if you’re interested and think you could fit, please don’t hesitate to apply.
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