Bibliography

Learn more from these resources relevant to Lyell’s approach and technologies.

  1. Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer

    Science, December 11, 2020

    DOI: 10.1126/science.abb9847

    Sri Krishna, Frank J. Lowery1, R. Copeland, Bahadiroglu, Ratnadeep Mukherjee, Li Jia, James T. Anibal, Abraham Sachs, Serifat O. Adebola, Devikala Gurusamy, Zhiya Yu, Victoria Hill, View Jared J. Gartner, Yong F. Li, Maria Parkhurst, Biman Paria, Pia Kvistborg, Michael C. Kelly, Stephanie L. Goff, Grégoire Altan-Bonnet, F. Robbins, Steven A. Rosenberg

  2. T cell stemness and dysfunction in tumors are triggered by a common mechanism

    Science, March 29, 2019

    DOI: 10.1126/science.aau0135

    Suman Kumar Vodnala, Robert Eil, Rigel J. Kishton, Madhusudhanan Sukumar, Tori N. Yamamoto, Ngoc-Han Ha, Ping-Hsien Lee, MinHwa Shin, Shashank J. Patel, Zhiya Yu, Douglas C. Palmer, Michael J. Kruhlak, Xiaojing Liu, Jason W. Locasale, Jing Huang, Rahul Roychoudhuri, Toren Finkel, Christopher A. Klebanoff, Nicholas P. Restifo

  3. c-Jun overexpression in CAR T cells induces exhaustion resistance

    Nature, December 4, 2019

    DOI: 10.1038/s41586-019-1805-z

    Rachel C. Lynn, Evan W. Weber, Elena Sotillo, David Gennert, Peng Xu, Zinaida Good, Hima Anbunathan, John Lattin, Robert Jones, Victor Tieu, Surya Nagaraja, Jeffrey Granja, Charles F. A. de Bourcy, Robbie Majzner, Ansuman T. Satpathy, Stephen R. Quake, Michelle Monje, Howard Y. Chang & Crystal L. Mackall

  4. Genetically engineered mouse models of cancer reveal new insights about the antitumor immune response

    Current Opinion in Immunology, March 4, 2013

    DOI: 10.1016/j.coi.2013.02.005

    Michel DuPage and Tyler Jacks

  5. Analysis of ROR1 Protein Expression in Human Cancer and Normal Tissues

    Clinical Cancer Research, November 16, 2016

    DOI: 10.1158/1078-0432.CCR-16-2083

    Ashwini Balakrishnan, Tracy Goodpaster, Julie Randolph-Habecker, Benjamin G. Hoffstrom, Florencia G. Jalikis, Lisa K. Koch, Carolina Berger, Paula L. Kosasih, Anusha Rajan, Daniel Sommermeyer, Peggy L. Porter, and Stanley R. Riddell

  6. Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells

    Cancer Immunology Research, October 29, 2014

    DOI: 10.1158/2326-6066.CIR-14-0163

    Carolina Berger, Daniel Sommermeyer, Michael Hudecek, Michael Berger, Ashwini Balakrishnan, Paulina J. Paszkiewicz, Paula L. Kosasih, Christoph Rader and Stanley R. Riddell

  7. Developmental Relationships of Four Exhausted CD8(+) T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

    Immunity, May 19, 2020

    DOI: 10.1016/j.immuni.2020.04.014

    Jean-Christophe Beltra, Sasikanth Manne, Mohamed S. Abdel-Hakeem, Makoto Kurachi, Josephine R. Giles, Zeyu Chen, Valentina Casella, Shin Foong Ngiow, Omar Khan, Yinghui Jane Huang, Patrick Yan, Kito Nzingha, Wei Xu, Ravi K. Amaravadi, Xiaowei Xu, Giorgos C. Karakousis, Tara C. Mitchell, Lynn M. Schuchter, Alexander C. Huang, E. John Wherry

  8. CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer

    Annual Review of Immunology, January 24, 2019

    DOI: 10.1146/annurev-immunol-041015-055318

    Laura M. McLane, Mohamed S. Abdel-Hakeem, and E. John Wherry

  9. TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8(+) T cell exhaustion

    National Academy of Sciences, June 18, 2019

    DOI: 10.1073/pnas.1905675116

    Hyungseok Seo, Joyce Chen, Edahí González-Avalos, Daniela Samaniego-Castruita, Arundhoti Das, Yueqiang H. Wang, Isaac F. López-Moyado, Romain O. Georges, Wade Zhang, Atsushi Onodera, Cheng-Jang Wu, Li-Fan Lu, Patrick G. Hogan, Avinash Bhandoola, and Anjana Rao

  10. NR4A transcription factors limit CAR T cell function in solid tumours

    Nature, February 27, 2019

    DOI: 10.1038/s41586-019-0985-x

    Joyce Chen, Isaac F. López-Moyado, Hyungseok Seo, Chan-Wang J. Lio, Laura J. Hempleman, Takashi Sekiya, Akihiko Yoshimura, James P. Scott-Browne & Anjana Rao

  11. Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

    Cancer Cell, February 28, 2021

    DOI: 10.1016/j.ccell.2020.11.005

    Shivani Srivastava 1, Scott N Furlan 2, Carla A Jaeger-Ruckstuhl 3, Megha Sarvothama 3, Carolina Berger 3, Kimberly S Smythe 3, Sarah M Garrison 3, Jennifer M Specht 4, Sylvia M Lee 4, Robert A Amezquita 5, Valentin Voillet 5, Vishaka Muhunthan 3, Sushma Yechan-Gunja 3, Smitha P S Pillai , Christoph Rader, A McGarry Houghton, Robert H Pierce 3, Raphael Gottardo 5, David G Maloney, Stanley R Riddell

  12. The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

    Nature Biotechnology, April 2014

    DOI: 10.1038/nbt.2859

    Cole Trapnell, Davide Cacchiarelli, Jonna Grimsby, Prapti Pokhare, Shuqiang Li, Michael Morse, Niall J Lennon, Kenneth J Livak, Tarjei S Mikkelsen, John L Rinn