Bibliography

1. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

Journal of Clinical Oncology, January 31, 2011

DOI: 10.1200/JCO.2010.32.2537

Paul F. Robbins , Richard A. Morgan , Steven A. Feldman , James C. Yang , Richard M. Sherry , Mark E. DudleyJohn R. Wunderlich , Azam V. Nahvi , Lee J. Helman , Crystal L. Mackall , Udai S. Kammula , Marybeth S. Hughes , Nicholas P. Restifo , Mark Raffeld , Chyi-Chia Richard Lee , Catherine L. Levy , Yong F. Li , Mona El-Gamil , Susan L. Schwarz , Carolyn Laurencot , Steven A. Rosenberg

2. A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response

Clinical Cancer Research, March 1, 2015

DOI: 10.1158/1078-0432.CCR-14-2708

Paul F Robbins, Sadik H Kassim, Thai L N Tran, Jessica S Crystal, Richard A Morgan, Steven A Feldman, James C Yang, Mark E Dudley, John R Wunderlich, Richard M Sherry, Udai S Kammula, Marybeth S Hughes, Nicholas P Restifo, Mark Raffeld, Chyi-Chia R Lee, Yong F Li, Mona El-Gamil, Steven A Rosenberg

3. Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3

Journal of Clinical Oncology, October 10, 2017

DOI:10.1200/JCO.2017.74.5463

Yong Chen Lu, Linda L. Parker, Tangying Lu, Zhili Zheng, Mary Ann Toomey, Donald E. White, Xin Yao, Yong F. Li, Paul F. Robbins, Steven A. Feldman, Pierre Van Der Bruggen, Christopher A. Klebanoff, Stephanie L. Goff, Richard M. Sherry, Udai S. Kammula, James C. Yang, Steven A. Rosenberg

4. Engineered T Cells Targeting E7 Mediate Regression of Human Papillomavirus Cancers in a Murine Model

JCI Insight, April 19, 2018

DOI:10.1172/jci.insight.99488

Benjamin Y. Jin, Tracy E. Campbell, Lindsey M. Draper, Sanja Stevanović, Bianca Weissbrich, Zhiya Yu, Nicholas P. Restifo, Steven A. Rosenberg, Cornelia L. Trimble, and Christian S. Hinrichs

5. Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma

Journal of Clinical Oncology, July 10, 2016

DOI:10.1200/JCO.2016.66.7220

Stephanie L. Goff, Deborah E. Citrin, Robert P. Somerville, John R. Wunderlich, David N. Danforth, James C. Yang, Richard M. Sherry, Udai S. Kammula, Christopher A. Klebanoff, Marybeth S. Hughes, Nicholas P. Restifo, Michelle M. Langhan, Thomas E. Shelton, Lily Lu, Mei Li M. Kwong, Sadia Ilyas, Nicholas D. Klemen, Eden C. Payabyab, Kathleen E. Morton, Mary Ann Toomey, Seth M. Steinberg, Donald E. White, and Steven A. Rosenberg

6. Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer

Science, April 14, 2017

DOI: 10.1126/science.aak9510

Sanja Stevanović, Anna Pasetto, Sarah R. Helman, Jared J. Gartner, Todd D. Prickett, Bryan Howie, Harlan S. Robins, Paul F. Robbins, Christopher A. Klebanoff, Steven A. Rosenberg, Christian S. Hinrichs

7. A randomized trial of adoptive immunotherapy with tumor-infiltrating lymphocytes and interleukin-2 versus standard therapy in the postoperative treatment of resected nonsmall cell lung carcinoma

Cancer, July 15, 1996

DOI:10.1002/(SICI)1097-0142(19960715)78:2<244::AID-CNCR9>3.0.CO;2-L

Giovanni B. Ratto, Paolo Zino, Sandro Mirabelli, Paolo Minuti, Riccardo Aquilina, Giovanni Fantino, Elisabetta Spessa, Marco Ponte, Paolo Bruzzi, Giovanni Melioli

8. Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

Nature Medicine, June 4, 2018

DOI:10.1038/s41591-018-0040-8

Nikolaos Zacharakis, Harshini Chinnasamy, Mary Black, Hui Xu, Yong-Chen Lu, Zhili Zheng, Anna Pasetto, Michelle Langhan, Thomas Shelton, Todd Prickett, Jared Gartner, Li Jia, Katarzyna Trebska-McGowan, Robert P. Somerville, Paul F. Robbins, Steven A. Rosenberg, Stephanie L. Goff & Steven A. Feldman

9. T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

New England Journal of Medicine, December 8, 2016

DOI:10.1056/NEJMoa1609279

Eric Tran, Ph.D., Paul F. Robbins, Ph.D., Yong-Chen Lu, Ph.D., Todd D. Prickett, Ph.D., Jared J. Gartner, M.Sc., Li Jia, M.Sc., Anna Pasetto, Ph.D., Zhili Zheng, Ph.D., Satyajit Ray, Ph.D., Eric M. Groh, M.D., Isaac R. Kriley, M.D., and Steven A. Rosenberg, M.D., Ph.D.

10. Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer

Science, May 9, 2014

DOI:10.1126/science.1251102

Eric Tran, Simon Turcotte, Alena Gros, Paul F. Robbins, Yong-Chen Lu, Mark E. Dudley, John R. Wunderlich, Robert P. Somerville, Katherine Hogan, Christian S. Hinrichs, Maria R. Parkhurst, James C. Yang, Steven A. Rosenberg

11. Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors

Nature, July 13, 2018

DOI:10.1038/s41467-018-05072-0

Thomas Duhen, Rebekka Duhen, Ryan Montler, Jake Moses, Tarsem Moudgil, Noel F. de Miranda, Cheri P. Goodall, Tiffany C. Blair, Bernard A. Fox, Jason E. McDermott, Shu-Ching Chang, Gary Grunkemeier, Rom Leidner, Richard Bryan Bell & Andrew D. Weinberg

12. Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients

Nature Medicine, February 22, 2016

DOI:10.1038/nm.4051

Alena Gros, Maria R Parkhurst, Eric Tran, Anna Pasetto, Paul F Robbins, Sadia Ilyas, Todd D Prickett, Jared J Gartner, Jessica S Crystal, Ilana M Roberts, Kasia Trebska-McGowan, John R Wunderlich, James C Yang, and Steven A Rosenberg

13. Bystander CD8(+) T cells are abundant and phenotypically distinct in human tumour infiltrates

Nature, May, 16, 2018

DOI:10.1038/s41586-018-0130-2

Yannick Simoni, Etienne Becht, Michael Fehlings, Chiew Yee Loh, Si-Lin Koo, Karen Wei Weng Teng, Joe Poh Sheng Yeong, Rahul Nahar, Tong Zhang, Hassen Kared, Kaibo Duan, Nicholas Ang, Michael Poidinger, Yin Yeng Lee, Anis Larbi, Alexis J. Khng, Emile Tan, Cherylin Fu, Ronnie Mathew, Melissa Teo, Wan Teck Lim, Chee Keong Toh, Boon-Hean Ong, Tina Koh, Axel M. Hillmer, Angela Takano, Tony Kiat Hon Lim, Eng Huat Tan, Weiwei Zhai, Daniel S. W. Tan, Iain Beehuat Tan & Evan W. Newell

14. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy Clinical Cancer Research, July 1, 2011

DOI:10.1158/1078-0432.CCR-11-0116

Steven A. Rosenberg, James C. Yang, Richard M. Sherry, Udai S. Kammula, Marybeth S. Hughes, Giao Q. Phan, Deborah E. Citrin, Nicholas P. Restifo, Paul F. Robbins, John R. Wunderlich, Kathleen E. Morton, Carolyn M. Laurencot, Seth M. Steinberg, Donald E. White, and Mark E. Dudley

15. Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer

Science, December 11, 2020

DOI: 10.1126/science.abb9847

Sri Krishna, Frank J. Lowery1, R. Copeland, Bahadiroglu, Ratnadeep Mukherjee, Li Jia, James T. Anibal, Abraham Sachs, Serifat O. Adebola, Devikala Gurusamy, Zhiya Yu, Victoria Hill, View Jared J. Gartner, Yong F. Li, Maria Parkhurst, Biman Paria, Pia Kvistborg, Michael C. Kelly, Stephanie L. Goff, Grégoire Altan-Bonnet, F. Robbins, Steven A. Rosenberg

16. Intratumoral Heterogeneity: More Than Just Mutations

Trends in Cell Biology, April 12, 2019

doi: 10.1016/j.tcb.2019.03.003

Kunihiko Hinohara, Kornelia Polyak

17. Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer

Cancer Discovery, December 28, 2016

doi:10.1158/2159-8290.CD-16-0828

Valsamo Anagnostou, Kellie N Smith, Patrick M Forde, Noushin Niknafs, Rohit Bhattacharya, James White, Theresa Zhang, Vilmos Adleff, Jillian Phallen, Neha Wali, Carolyn Hruban, Violeta B Guthrie, Kristen Rodgers, Jarushka Naidoo, Hyunseok Kang, William Sharfman, Christos Georgiades, Franco Verde, Peter Illei, Qing Kay Li, Edward Gabrielson, Malcolm V Brock, Cynthia A Zahnow, Stephen B Baylin, Robert B Scharpf, Julie R Brahmer, Rachel Karchin, Drew M Pardoll, Victor E Velculescu

18. TCR Repertoire Changes during TIL Expansion: Clonal Selection or Drifting?

Clinical Cancer Research, June 9, 2020

doi:10.1158/1078-0432.CCR-20-1560

Maria Lozano-Rabella and Alena Gros

19. T cell stemness and dysfunction in tumors are triggered by a common mechanism

Science, March 29, 2019

DOI:10.1126/science.aau0135

Suman Kumar Vodnala, Robert Eil, Rigel J. Kishton, Madhusudhanan Sukumar, Tori N. Yamamoto, Ngoc-Han Ha, Ping-Hsien Lee, MinHwa Shin, Shashank J. Patel, Zhiya Yu, Douglas C. Palmer, Michael J. Kruhlak, Xiaojing Liu, Jason W. Locasale, Jing Huang, Rahul Roychoudhuri, Toren Finkel, Christopher A. Klebanoff, Nicholas P. Restifo

20. c-Jun overexpression in CAR T cells induces exhaustion resistance

Nature, December 4, 2019

DOI:10.1038/s41586-019-1805-z

Rachel C. Lynn, Evan W. Weber, Elena Sotillo, David Gennert, Peng Xu, Zinaida Good, Hima Anbunathan, John Lattin, Robert Jones, Victor Tieu, Surya Nagaraja, Jeffrey Granja, Charles F. A. de Bourcy, Robbie Majzner, Ansuman T. Satpathy, Stephen R. Quake, Michelle Monje, Howard Y. Chang & Crystal L. Mackall

21. Genetically engineered mouse models of cancer reveal new insights about the antitumor immune response

Current Opinion in Immunology, March 4, 2013

doi:10.1016/j.coi.2013.02.005

Michel DuPage and Tyler Jacks

22. Analysis of ROR1 Protein Expression in Human Cancer and Normal Tissues

Clinical Cancer Research, November 16, 2016

DOI: 10.1158/1078-0432.CCR-16-2083

Ashwini Balakrishnan, Tracy Goodpaster, Julie Randolph-Habecker, Benjamin G. Hoffstrom, Florencia G. Jalikis, Lisa K. Koch, Carolina Berger, Paula L. Kosasih, Anusha Rajan, Daniel Sommermeyer, Peggy L. Porter, and Stanley R. Riddell

23. Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells

Cancer Immunology Research, October 29, 2014

DOI:10.1158/2326-6066.CIR-14-0163

Carolina Berger, Daniel Sommermeyer, Michael Hudecek, Michael Berger, Ashwini Balakrishnan, Paulina J. Paszkiewicz, Paula L. Kosasih, Christoph Rader and Stanley R. Riddell

24. Developmental Relationships of Four Exhausted CD8(+) T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

Immunity, May 19, 2020

DOI: 10.1016/j.immuni.2020.04.014

Jean-Christophe Beltra, Sasikanth Manne, Mohamed S. Abdel-Hakeem, Makoto Kurachi, Josephine R. Giles, Zeyu Chen, Valentina Casella, Shin Foong Ngiow, Omar Khan, Yinghui Jane Huang, Patrick Yan, Kito Nzingha, Wei Xu, Ravi K. Amaravadi, Xiaowei Xu, Giorgos C. Karakousis, Tara C. Mitchell, Lynn M. Schuchter, Alexander C. Huang, E. John Wherry

25. CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer

Annual Review of Immunology, January 24, 2019

doi: 10.1146/annurev-immunol-041015-055318

Laura M. McLane, Mohamed S. Abdel-Hakeem, and E. John Wherry

26. TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8(+) T cell exhaustion

National Academy of Sciences, June 18, 2019

DOI: 10.1073/pnas.1905675116

Hyungseok Seo, Joyce Chen, Edahí González-Avalos, Daniela Samaniego-Castruita, Arundhoti Das, Yueqiang H. Wang, Isaac F. López-Moyado, Romain O. Georges, Wade Zhang, Atsushi Onodera, Cheng-Jang Wu, Li-Fan Lu, Patrick G. Hogan, Avinash Bhandoola, and Anjana Rao

27. NR4A transcription factors limit CAR T cell function in solid tumours

Nature, February 27, 2019

DOI: 10.1038/s41586-019-0985-x

Joyce Chen, Isaac F. López-Moyado, Hyungseok Seo, Chan-Wang J. Lio, Laura J. Hempleman, Takashi Sekiya, Akihiko Yoshimura, James P. Scott-Browne & Anjana Rao

28. Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

Cancer Cell, February 28, 2021

doi: 10.1016/j.ccell.2020.11.005

Shivani Srivastava 1, Scott N Furlan 2, Carla A Jaeger-Ruckstuhl 3, Megha Sarvothama 3, Carolina Berger 3, Kimberly S Smythe 3, Sarah M Garrison 3, Jennifer M Specht 4, Sylvia M Lee 4, Robert A Amezquita 5, Valentin Voillet 5, Vishaka Muhunthan 3, Sushma Yechan-Gunja 3, Smitha P S Pillai , Christoph Rader, A McGarry Houghton, Robert H Pierce 3, Raphael Gottardo 5, David G Maloney, Stanley R Riddell

29. The epigenetic landscape of T cell exhaustion

Science, October 27, 2016

DOI: 10.1126/science.aae0491

Debattama R. Sen, James Kaminski, R. Anthony Barnitz, Makoto Kurachi, Ulrike Gerdemann, Kathleen B. Yates, Hsiao-Wei Tsao, Jernej Godec, Martin W. LaFleur, Flavian D. Brown, Pierre Tonnerre, Raymond T. Chung, Damien C. Tully, Todd M. Allen, Nicole Frahm, Georg M. Lauer, E. John Wherry, Nir Yosef, W. Nicholas Haining

30. Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8 T Cells

Journal of Experimental Medicine, August 18, 2003

DOI: 10.1084/jem.20030590

Willem W. Overwijk , Marc R. Theoret , Steven E. Finkelstein , Deborah R. Surman , Laurina A. de Jong , Florry A. Vyth-Dreese , Trees A. Dellemijn , Paul A. Antony , Paul J. Spiess , Douglas C. Palmer , David M. Heimann , Christopher A. Klebanoff , Zhiya Yu , Leroy N. Hwang , Lionel Feigenbaum , Ada M. Kruisbeek , Steven A. Rosenberg, Nicholas P. Restifo

31. The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Nature Biotechnology, April 2014

DOI: 10.1038/nbt.2859

Cole Trapnell, Davide Cacchiarelli, Jonna Grimsby, Prapti Pokhare, Shuqiang Li, Michael Morse, Niall J Lennon, Kenneth J Livak, Tarjei S Mikkelsen, John L Rinn